Sigma 1 Receptor Co-Localizes with NRF2 in Retinal Photoreceptor Cells

Sigma 1 receptor (Sig1R), a modulator of cell survival, has emerged as a novel target for retinal degenerative disease. Studies have shown that activation of Sig1R, using the high affinity ligand (+)-pentazocine ((+)-PTZ), improves cone function in a severe retinopathy model. The rescue is accompani...

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Detalles Bibliográficos
Autores principales: Barwick, Shannon R., Siddiq, Mevish S., Wang, Jing, Xiao, Haiyan, Marshall, Brendan, Perry, Elizabeth, Smith, Sylvia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234060/
https://www.ncbi.nlm.nih.gov/pubmed/34205384
http://dx.doi.org/10.3390/antiox10060981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234060/
https://www.ncbi.nlm.nih.gov/pubmed/34205384
http://dx.doi.org/10.3390/antiox10060981

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