Cargando…
Sigma 1 Receptor Co-Localizes with NRF2 in Retinal Photoreceptor Cells
Sigma 1 receptor (Sig1R), a modulator of cell survival, has emerged as a novel target for retinal degenerative disease. Studies have shown that activation of Sig1R, using the high affinity ligand (+)-pentazocine ((+)-PTZ), improves cone function in a severe retinopathy model. The rescue is accompani...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234060/ https://www.ncbi.nlm.nih.gov/pubmed/34205384 http://dx.doi.org/10.3390/antiox10060981 |