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Preclinical In Vitro Studies with 3D Spheroids to Evaluate Cu(DDC)(2) Containing Liposomes for the Treatment of Neuroblastoma

Preclinical in vitro studies of drug candidates for anticancer therapy are generally conducted on well-established 2D cell models. Unfortunately, these models are unable to mimic the properties of in vivo tumors. However, in vitro 3D models (spheroids) have been proven to be superior in reflecting t...

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Detalles Bibliográficos
Autores principales: Hartwig, Friederike, Köll-Weber, Monika, Süss, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234124/
https://www.ncbi.nlm.nih.gov/pubmed/34204205
http://dx.doi.org/10.3390/pharmaceutics13060894