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SUN-MKL1 Crosstalk Regulates Nuclear Deformation and Fast Motility of Breast Carcinoma Cells in Fibrillar ECM Microenvironment

Aligned collagen fibers provide topography for the rapid migration of single tumor cells (streaming migration) to invade the surrounding stroma, move within tumor nests towards blood vessels to intravasate and form distant metastases. Mechanisms of tumor cell motility have been studied extensively i...

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Detalles Bibliográficos
Autores principales: Sharma, Ved P., Williams, James, Leung, Edison, Sanders, Joe, Eddy, Robert, Castracane, James, Oktay, Maja H., Entenberg, David, Condeelis, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234170/
https://www.ncbi.nlm.nih.gov/pubmed/34205257
http://dx.doi.org/10.3390/cells10061549