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Targeting CDK9 for the Treatment of Glioblastoma

SIMPLE SUMMARY: Inhibition of cyclin-dependent kinase 9 (CDK9) can impact multiple survival pathways in cancers and may be a promising therapeutic approach for glioblastoma, which is known to be highly resistant to treatments and thus challenging to treat. This review assesses the mechanisms by whic...

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Detalles Bibliográficos
Autores principales: Ranjan, Alice, Pang, Ying, Butler, Madison, Merchant, Mythili, Kim, Olga, Yu, Guangyang, Su, Yu-Ting, Gilbert, Mark R., Levens, David, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234280/
https://www.ncbi.nlm.nih.gov/pubmed/34207158
http://dx.doi.org/10.3390/cancers13123039