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Interleukin‐18, IL‐18 binding protein and IL‐18 receptor expression in asthma: a hypothesis showing IL‐18 promotes epithelial cell differentiation

OBJECTIVE: In asthma, genome‐wide association studies have shown that interleukin‐18 (IL‐18) receptor 1 gene (IL‐18R1) and sputum IL‐18 are increased during exacerbations. However, the role of the IL‐18 axis in bronchial epithelial function is unclear. To investigate IL‐18, IL‐18 binding protein (BP...

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Detalles Bibliográficos
Autores principales: Kaur, Davinder, Chachi, Latifa, Gomez, Edith, Sylvius, Nicolas, Brightling, Christopher E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234286/
https://www.ncbi.nlm.nih.gov/pubmed/34194747
http://dx.doi.org/10.1002/cti2.1301