Null cyp1b1 Activity in Zebrafish Leads to Variable Craniofacial Defects Associated with Altered Expression of Extracellular Matrix and Lipid Metabolism Genes

SIMPLE SUMMARY: CYP1B1 is a cytochrome P450 monooxygenase involved in oxidative metabolism of different endogenous lipids and drugs. The loss of function (LoF) of this gene underlies many cases of recessive primary congenital glaucoma (PCG), an infrequent disease and a common cause of infantile loss...

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Detalles Bibliográficos
Autores principales: Alexandre-Moreno, Susana, Bonet-Fernández, Juan-Manuel, Atienzar-Aroca, Raquel, Aroca-Aguilar, José-Daniel, Escribano, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234340/
https://www.ncbi.nlm.nih.gov/pubmed/34208498
http://dx.doi.org/10.3390/ijms22126430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234340/
https://www.ncbi.nlm.nih.gov/pubmed/34208498
http://dx.doi.org/10.3390/ijms22126430

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