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Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis

Zebrafish embryos (ZFE) have increasingly gained in popularity as a model to perform safety screenings of compounds. Although immersion of ZFE is the main route of exposure used, evidence shows that not all small molecules are equally absorbed, possibly resulting in false-negative readouts and incor...

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Detalles Bibliográficos
Autores principales: Guarin, Marlly, Ny, Annelii, De Croze, Noémie, Maes, Jan, Léonard, Marc, Annaert, Pieter, de Witte, Peter A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234359/
https://www.ncbi.nlm.nih.gov/pubmed/34208572
http://dx.doi.org/10.3390/ph14060576