A Metabolic Change towards Fermentation Drives Cancer Cachexia in Myotubes

Cachexia is a disorder associated with several pathologies, including cancer. In this paper, we describe how cachexia is induced in myotubes by a metabolic shift towards fermentation, and the block of this metabolic modification prevents the onset of the cachectic phenotype. Cachectic myotubes, obta...

Descripción completa

Detalles Bibliográficos
Autores principales: Mannelli, Michele, Gamberi, Tania, Magherini, Francesca, Fiaschi, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234377/
https://www.ncbi.nlm.nih.gov/pubmed/34203023
http://dx.doi.org/10.3390/biomedicines9060698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234377/
https://www.ncbi.nlm.nih.gov/pubmed/34203023
http://dx.doi.org/10.3390/biomedicines9060698

Ejemplares similares