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Structural Analysis of a Genetically Encoded FRET Biosensor by SAXS and MD Simulations

Inspired by the modular architecture of natural signaling proteins, ligand binding proteins are equipped with two fluorescent proteins (FPs) in order to obtain Förster resonance energy transfer (FRET)-based biosensors. Here, we investigated a glucose sensor where the donor and acceptor FPs were atta...

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Detalles Bibliográficos
Autores principales: Reinartz, Ines, Sarter, Mona, Otten, Julia, Höfig, Henning, Pohl, Martina, Schug, Alexander, Stadler, Andreas M., Fitter, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234384/
https://www.ncbi.nlm.nih.gov/pubmed/34208740
http://dx.doi.org/10.3390/s21124144