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Microelectromechanical System Measurement of Platelet Contraction: Direct Interrogation of Myosin Light Chain Phosphorylation

Myosin Light Chain (MLC) regulates platelet contraction through its phosphorylation by Myosin Light Chain Kinase (MLCK) or dephosphorylation by Myosin Light Chain Phosphatase (MLCP). The correlation between platelet contraction force and levels of MLC phosphorylation is unknown. We investigate the r...

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Detalles Bibliográficos
Autores principales: George, Mitchell J., Litvinov, Julia, Aroom, Kevin, Spangler, Leland J., Caplan, Henry, Wade, Charles E., Cox, Charles S., Gill, Brijesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234414/
https://www.ncbi.nlm.nih.gov/pubmed/34208643
http://dx.doi.org/10.3390/ijms22126448