The Anti-Tumor Activity of the NEDD8 Inhibitor Pevonedistat in Neuroblastoma

Pevonedistat is a neddylation inhibitor that blocks proteasomal degradation of cullin–RING ligase (CRL) proteins involved in the degradation of short-lived regulatory proteins, including those involved with cell-cycle regulation. We determined the sensitivity and mechanism of action of pevonedistat...

Descripción completa

Detalles Bibliográficos
Autores principales: Foster, Jennifer H., Barbieri, Eveline, Zhang, Linna, Scorsone, Kathleen A., Moreno-Smith, Myrthala, Zage, Peter, Horton, Terzah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234433/
https://www.ncbi.nlm.nih.gov/pubmed/34207315
http://dx.doi.org/10.3390/ijms22126565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234433/
https://www.ncbi.nlm.nih.gov/pubmed/34207315
http://dx.doi.org/10.3390/ijms22126565

Ejemplares similares