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Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma

SIMPLE SUMMARY: Cyclophilins, a family of proteins with peptidyl prolyl isomerase activity, have been found to be overexpressed in several cancers, including hepatocellular carcinoma (HCC), and their expression is correlated to a poor prognosis. Cyclophilins play an important role in proliferation a...

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Detalles Bibliográficos
Autores principales: Simón Serrano, Sonia, Tavecchio, Michele, Grönberg, Alvar, Sime, Wondossen, Jemaà, Mohamed, Moss, Steven, Gregory, Matthew Alan, Gallay, Philippe, Elmér, Eskil, Hansson, Magnus Joakim, Massoumi, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234462/
https://www.ncbi.nlm.nih.gov/pubmed/34207224
http://dx.doi.org/10.3390/cancers13123041