The Fumarprotocetraric Acid Inhibits Tau Covalently, Avoiding Cytotoxicity of Aggregates in Cells

Neurodegenerative disorders, including Tauopathies that involve tau protein, base their pathological mechanism on forming proteinaceous aggregates, which has a deleterious effect on cells triggering an inflammatory response. Moreover, tau inhibitors can exert their mechanism of action through noncov...

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Detalles Bibliográficos
Autores principales: González, Camila, Cartagena, Constanza, Caballero, Leonardo, Melo, Francisco, Areche, Carlos, Cornejo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234475/
https://www.ncbi.nlm.nih.gov/pubmed/34205516
http://dx.doi.org/10.3390/molecules26123760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234475/
https://www.ncbi.nlm.nih.gov/pubmed/34205516
http://dx.doi.org/10.3390/molecules26123760

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