Polyhydroxyalkanoate/Antifungal Polyene Formulations with Monomeric Hydroxyalkanoic Acids for Improved Antifungal Efficiency

Novel biodegradable and biocompatible formulations of “old” but “gold” drugs such as nystatin (Nys) and amphotericin B (AmB) were made using a biopolymer as a matrix. Medium chain length polyhydroxyalkanoates (mcl-PHA) were used to formulate both polyenes (Nys and AmB) in the form of films (~50 µm)....

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Detalles Bibliográficos
Autores principales: Pekmezovic, Marina, Kalagasidis Krusic, Melina, Malagurski, Ivana, Milovanovic, Jelena, Stępień, Karolina, Guzik, Maciej, Charifou, Romina, Babu, Ramesh, O’Connor, Kevin, Nikodinovic-Runic, Jasmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234488/
https://www.ncbi.nlm.nih.gov/pubmed/34207011
http://dx.doi.org/10.3390/antibiotics10060737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234488/
https://www.ncbi.nlm.nih.gov/pubmed/34207011
http://dx.doi.org/10.3390/antibiotics10060737

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