Mutant p53(L194F) Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to Mortaparib(Plus), a Multimodal Small Molecule Inhibitor

SIMPLE SUMMARY: Tumor suppressor protein p53 is a master regulator that inhibits the process of oncogenesis by induction of cell senescence/cell cycle arrest/apoptosis during normal and stressed states of cells. It is functionally inactivated in the majority of cancers. Mortalin, a member of the Hsp...

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Detalles Bibliográficos
Autores principales: Elwakeel, Ahmed, Sari, Anissa Nofita, Dhanjal, Jaspreet Kaur, Meidinna, Hazna Noor, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234533/
https://www.ncbi.nlm.nih.gov/pubmed/34207240
http://dx.doi.org/10.3390/cancers13123043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234533/
https://www.ncbi.nlm.nih.gov/pubmed/34207240
http://dx.doi.org/10.3390/cancers13123043

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