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Distinct Characteristics and Clinical Outcomes to Predict the Emergence of MET Amplification in Patients with Non-Small Cell Lung Cancer Who Developed Resistance after Treatment with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

SIMPLE SUMMARY: MET amplification is one of the resistance determinants after EGFR-TKI therapy in EGFR mutant NSCLC. In this study, we evaluated the emergence of MET amplification after EGFR-TKI treatment failure. The median progression-free survival associated with the most recent EGFR-TKI treatmen...

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Detalles Bibliográficos
Autores principales: Ahn, Beung-Chul, Lee, Ji Hyun, Kim, Min Hwan, Pyo, Kyoung-Ho, Lee, Choong-kun, Lim, Sun Min, Kim, Hye Ryun, Cho, Byoung Chul, Hong, Min Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234556/
https://www.ncbi.nlm.nih.gov/pubmed/34205733
http://dx.doi.org/10.3390/cancers13123096