Balancing the CD38 Expression on Effector and Target Cells in Daratumumab-Mediated NK Cell ADCC against Multiple Myeloma

SIMPLE SUMMARY: We tracked the cytotoxic potential of NK cells towards multiple myeloma cells in daratumumab-mediated antibody-dependent cellular cytotoxicity assays. These cytotoxicity levels could be directly correlated to the expression of the target antigen (CD38) and to the percentage of fratri...

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Detalles Bibliográficos
Autores principales: Lejeune, Margaux, Duray, Elodie, Peipp, Matthias, Clémenceau, Béatrice, Baron, Frédéric, Beguin, Yves, Caers, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234557/
https://www.ncbi.nlm.nih.gov/pubmed/34203012
http://dx.doi.org/10.3390/cancers13123072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234557/
https://www.ncbi.nlm.nih.gov/pubmed/34203012
http://dx.doi.org/10.3390/cancers13123072

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