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The Influence of Drug–Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles

In this study, laser-induced in situ amorphization (i.e., amorphization inside the final dosage form) of the model drug celecoxib (CCX) with six different polymers was investigated. The drug–polymer combinations were studied with regard to the influence of (i) the physicochemical properties of the p...

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Detalles Bibliográficos
Autores principales: Hempel, Nele-Johanna, Merkl, Padryk, Knopp, Matthias Manne, Berthelsen, Ragna, Teleki, Alexandra, Sotiriou, Georgios A., Löbmann, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234654/
https://www.ncbi.nlm.nih.gov/pubmed/34205754
http://dx.doi.org/10.3390/pharmaceutics13060917