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Inhibition of P2X7 Purinergic Receptor Ameliorates Fibromyalgia Syndrome by Suppressing NLRP3 Pathway

Fibromyalgia is a chronic condition characterized by persistent widespread pain that significantly reduces quality of life in patients. The purinergic P2X7 receptor (P2X7R) seems to be involved in different pain states and neuroinflammation. The purpose of this study is to investigate the positive e...

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Detalles Bibliográficos
Autores principales: D’Amico, Ramona, Fusco, Roberta, Siracusa, Rosalba, Impellizzeri, Daniela, Peritore, Alessio Filippo, Gugliandolo, Enrico, Interdonato, Livia, Sforza, Andrea Maria, Crupi, Rosalia, Cuzzocrea, Salvatore, Genovese, Tiziana, Cordaro, Marika, Di Paola, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234677/
https://www.ncbi.nlm.nih.gov/pubmed/34208781
http://dx.doi.org/10.3390/ijms22126471