Paracrine Kynurenic Pathway Activation in the Bone of Young Uremic Rats Can Antagonize Anabolic Effects of PTH on Bone Turnover and Strength through the Disruption of PTH-Dependent Molecular Signaling

Secondary hyperparathyroidism and abnormalities in tryptophan (TRP) metabolism are commonly observed in chronic kidney disease (CKD). The present study aimed to establish potential interactions between endogenous parathyroid hormone (PTH) and activation of the bone kynurenine (KYN) pathway in relati...

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Detalles Bibliográficos
Autores principales: Pawlak, Krystyna, Sieklucka, Beata, Pawlak, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234704/
https://www.ncbi.nlm.nih.gov/pubmed/34207309
http://dx.doi.org/10.3390/ijms22126563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234704/
https://www.ncbi.nlm.nih.gov/pubmed/34207309
http://dx.doi.org/10.3390/ijms22126563

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