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Soluble Cytoplasmic Expression and Purification of Immunotoxin HER2(scFv)-PE24B as a Maltose Binding Protein Fusion

Human epidermal growth factor receptor 2 (HER-2) is overexpressed in many malignant tumors. The anti-HER2 antibody trastuzumab has been approved for treating HER2-positive early and metastatic breast cancers. Pseudomonas exotoxin A (PE), a bacterial toxin of Pseudomonas aeruginosa, consists of an A-...

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Detalles Bibliográficos
Autores principales: Park, Sangsu, Nguyen, Minh Quan, Ta, Huynh Kim Khanh, Nguyen, Minh Tan, Lee, Gunsup, Kim, Chong Jai, Jang, Yeon Jin, Choe, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234717/
https://www.ncbi.nlm.nih.gov/pubmed/34204265
http://dx.doi.org/10.3390/ijms22126483