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Preconceptional Immunization Can Modulate Offspring Intrathymic IL-17-Producing γδT Cells with Epigenetic Implications Mediated by microRNAs

The mechanisms through which maternal immunization can modulate offspring thymic maturation of lymphocytes are not fully understood. Here, we aimed to evaluate whether maternal OVA-immunization can inhibit the maturation of IL-17-producing γδT cells in offspring thymus, and if this mechanism has epi...

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Detalles Bibliográficos
Autores principales: de-Sousa, Thamires Rodrigues, Pessôa, Rodrigo, Nascimento, Andrezza, Fagundes, Beatriz Oliveira, Sgnotto, Fábio da Ressureição, Duarte, Alberto José da Silva, Sanabani, Sabri Saeed, Victor, Jefferson Russo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234718/
https://www.ncbi.nlm.nih.gov/pubmed/34205753
http://dx.doi.org/10.3390/ijms22126633