Functional Characterization of Two Novel Mutations in SCN5A Associated with Brugada Syndrome Identified in Italian Patients

Background. Brugada syndrome (BrS) is an autosomal dominantly inherited cardiac disease characterized by “coved type” ST-segment elevation in the right precordial leads, high susceptibility to ventricular arrhythmia and a family history of sudden cardiac death. The SCN5A gene, encoding for the cardi...

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Detalles Bibliográficos
Autores principales: Balla, Cristina, Conte, Elena, Selvatici, Rita, Marsano, Renè Massimiliano, Gerbino, Andrea, Farnè, Marianna, Blunck, Rikard, Vitali, Francesco, Armaroli, Annarita, Brieda, Alessandro, Liantonio, Antonella, De Luca, Annamaria, Ferlini, Alessandra, Rapezzi, Claudio, Bertini, Matteo, Gualandi, Francesca, Imbrici, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234720/
https://www.ncbi.nlm.nih.gov/pubmed/34204499
http://dx.doi.org/10.3390/ijms22126513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234720/
https://www.ncbi.nlm.nih.gov/pubmed/34204499
http://dx.doi.org/10.3390/ijms22126513

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