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Immunoglobulin germline gene variation and its impact on human disease

Immunoglobulins (Ig) play an important role in the immune system both when expressed as antigen receptors on the cell surface of B cells and as antibodies secreted into extracellular fluids. The advent of high-throughput sequencing methods has enabled the investigation of human Ig repertoires at unp...

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Detalles Bibliográficos
Autores principales: Mikocziova, Ivana, Greiff, Victor, Sollid, Ludvig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234759/
https://www.ncbi.nlm.nih.gov/pubmed/34175903
http://dx.doi.org/10.1038/s41435-021-00145-5