The Exon Junction Complex Core Represses Cancer-Specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing

Using TSG101 pre-mRNA, we previously discovered cancer-specific re-splicing of mature mRNA that generates aberrant transcripts/proteins. The fact that mRNA is aberrantly re-spliced in various cancer cells implies there must be an important mechanism to prevent deleterious re-splicing on the spliced...

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Detalles Bibliográficos
Autores principales: Otani, Yuta, Fujita, Ken-ichi, Kameyama, Toshiki, Mayeda, Akila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234774/
https://www.ncbi.nlm.nih.gov/pubmed/34204574
http://dx.doi.org/10.3390/ijms22126519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234774/
https://www.ncbi.nlm.nih.gov/pubmed/34204574
http://dx.doi.org/10.3390/ijms22126519

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