Induction of Tertiary Phase Epileptiform Discharges after Postasphyxial Infusion of a Toll-Like Receptor 7 Agonist in Preterm Fetal Sheep

Background: Toll-like receptor (TLR) agonists are key immunomodulatory factors that can markedly ameliorate or exacerbate hypoxic–ischemic brain injury. We recently demonstrated that central infusion of the TLR7 agonist Gardiquimod (GDQ) following asphyxia was highly neuroprotective after 3 days but...

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Detalles Bibliográficos
Autores principales: Cho, Kenta H.T., Fraser, Mhoyra, Xu, Bing, Dean, Justin M., Gunn, Alistair J., Bennet, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234830/
https://www.ncbi.nlm.nih.gov/pubmed/34205464
http://dx.doi.org/10.3390/ijms22126593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234830/
https://www.ncbi.nlm.nih.gov/pubmed/34205464
http://dx.doi.org/10.3390/ijms22126593

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