Cargando…
Induction of Tertiary Phase Epileptiform Discharges after Postasphyxial Infusion of a Toll-Like Receptor 7 Agonist in Preterm Fetal Sheep
Background: Toll-like receptor (TLR) agonists are key immunomodulatory factors that can markedly ameliorate or exacerbate hypoxic–ischemic brain injury. We recently demonstrated that central infusion of the TLR7 agonist Gardiquimod (GDQ) following asphyxia was highly neuroprotective after 3 days but...
Autores principales: | Cho, Kenta H.T., Fraser, Mhoyra, Xu, Bing, Dean, Justin M., Gunn, Alistair J., Bennet, Laura |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234830/ https://www.ncbi.nlm.nih.gov/pubmed/34205464 http://dx.doi.org/10.3390/ijms22126593 |
Ejemplares similares
-
Protective effects of delayed intraventricular TLR7 agonist administration on cerebral white and gray matter following asphyxia in the preterm fetal sheep
por: Cho, Kenta H. T., et al.
Publicado: (2019) -
Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep
por: van den Heuij, Lotte G, et al.
Publicado: (2014) -
Effects of delayed intraventricular TLR7 agonist administration on long-term neurological outcome following asphyxia in the preterm fetal sheep
por: Cho, Kenta H. T., et al.
Publicado: (2020) -
Tumor necrosis factor inhibition attenuates white matter gliosis after systemic inflammation in preterm fetal sheep
por: Galinsky, Robert, et al.
Publicado: (2020) -
LPS and TNF alpha modulate AMPA/NMDA receptor subunit expression and induce PGE2 and glutamate release in preterm fetal ovine mixed glial cultures
por: Weaver-Mikaere, Luke, et al.
Publicado: (2013)