Structural Chromosome Instability: Types, Origins, Consequences, and Therapeutic Opportunities

SIMPLE SUMMARY: Chromosome instability (CIN) is characterized by an increased accumulation of numerical and structural changes in chromosomes and is a common feature of solid tumors and some hematological malignancies. CIN has been extensively linked to tumorigenesis, cancer progression, and tumor r...

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Detalles Bibliográficos
Autores principales: Siri, Sebastián Omar, Martino, Julieta, Gottifredi, Vanesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234978/
https://www.ncbi.nlm.nih.gov/pubmed/34205328
http://dx.doi.org/10.3390/cancers13123056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234978/
https://www.ncbi.nlm.nih.gov/pubmed/34205328
http://dx.doi.org/10.3390/cancers13123056

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