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Structural Chromosome Instability: Types, Origins, Consequences, and Therapeutic Opportunities

SIMPLE SUMMARY: Chromosome instability (CIN) is characterized by an increased accumulation of numerical and structural changes in chromosomes and is a common feature of solid tumors and some hematological malignancies. CIN has been extensively linked to tumorigenesis, cancer progression, and tumor r...

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Detalles Bibliográficos
Autores principales:	Siri, Sebastián Omar, Martino, Julieta, Gottifredi, Vanesa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234978/ https://www.ncbi.nlm.nih.gov/pubmed/34205328 http://dx.doi.org/10.3390/cancers13123056

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