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Optogenetically Controlled Activity Pattern Determines Survival Rate of Developing Neocortical Neurons

A substantial proportion of neurons undergoes programmed cell death (apoptosis) during early development. This process is attenuated by increased levels of neuronal activity and enhanced by suppression of activity. To uncover whether the mere level of activity or also the temporal structure of elect...

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Detalles Bibliográficos
Autores principales: Wong Fong Sang, I. Emeline, Schroer, Jonas, Halbhuber, Lisa, Warm, Davide, Yang, Jenq-Wei, Luhmann, Heiko J., Kilb, Werner, Sinning, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235092/
https://www.ncbi.nlm.nih.gov/pubmed/34205237
http://dx.doi.org/10.3390/ijms22126575