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From Stem Cells to Populations—Using hiPSC, Next-Generation Sequencing, and GWAS to Explore the Genetic and Molecular Mechanisms of Congenital Heart Defects

Congenital heart defects (CHD) are developmental malformations affecting the heart and the great vessels. Early heart development requires temporally regulated crosstalk between multiple cell types, signaling pathways, and mechanical forces of early blood flow. While both genetic and environmental f...

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Detalles Bibliográficos
Autores principales: Broberg, Martin, Hästbacka, Johanna, Helle, Emmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235101/
https://www.ncbi.nlm.nih.gov/pubmed/34208537
http://dx.doi.org/10.3390/genes12060921