Persistence of CRISPR/Cas9 gene edited hematopoietic stem cells following transplantation: A systematic review and meta‐analysis of preclinical studies

Gene editing blood‐derived cells is an attractive approach to cure selected monogenic diseases but remains experimental. A systematic search of preclinical controlled studies is needed to determine the persistence of edited cells following reinfusion. All studies identified in our systematic search...

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Detalles Bibliográficos
Autores principales: Maganti, Harinad B., Bailey, Adrian J. M., Kirkham, Aidan M., Shorr, Risa, Pineault, Nicolas, Allan, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Concise Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235122/
https://www.ncbi.nlm.nih.gov/pubmed/33666363
http://dx.doi.org/10.1002/sctm.20-0520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235122/
https://www.ncbi.nlm.nih.gov/pubmed/33666363
http://dx.doi.org/10.1002/sctm.20-0520

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