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High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling

To harness the full potential of human pluripotent stem cells (hPSCs) we combined instrumented stirred tank bioreactor (STBR) technology with the power of in silico process modeling to overcome substantial, hPSC‐specific hurdles toward their mass production. Perfused suspension culture (3D) of matri...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Manstein, Felix, Ullmann, Kevin, Kropp, Christina, Halloin, Caroline, Triebert, Wiebke, Franke, Annika, Farr, Clara‐Milena, Sahabian, Anais, Haase, Alexandra, Breitkreuz, Yannik, Peitz, Michael, Brüstle, Oliver, Kalies, Stefan, Martin, Ulrich, Olmer, Ruth, Zweigerdt, Robert
Μορφή: Online Άρθρο Κείμενο
Γλώσσα:English
Έκδοση: John Wiley & Sons, Inc. 2021
Θέματα:
Διαθέσιμο Online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235132/
https://www.ncbi.nlm.nih.gov/pubmed/33660952
http://dx.doi.org/10.1002/sctm.20-0453