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Eritoran Attenuates Hepatic Inflammation and Fibrosis in Mice with Chronic Liver Injury

Toll-like receptor 4 (TLR4) signaling plays a key role in liver inflammation and fibrosis. The therapeutic effects of eritoran, a TLR4 antagonist, in mice with chronic liver injury remained unclear. C57BL/6 mice were fed a fast-food diet (FFD) or treated with carbon tetrachloride (CCl(4)) to induce...

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Detalles Bibliográficos
Autores principales: Hsieh, Yun-Cheng, Lee, Kuei-Chuan, Wu, Pei-Shan, Huo, Teh-Ia, Huang, Yi-Hsiang, Hou, Ming-Chih, Lin, Han-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235164/
https://www.ncbi.nlm.nih.gov/pubmed/34205789
http://dx.doi.org/10.3390/cells10061562