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Tumor Microenvironment-Responsive Shell/Core Composite Nanoparticles for Enhanced Stability and Antitumor Efficiency Based on a pH-Triggered Charge-Reversal Mechanism

High systemic stability and effective tumor accumulation of chemotherapeutic agents are indispensable elements that determine their antitumor efficacy. PEGylation of nanoparticles (NPs) could prolong the retention time in vivo by improving their stability in circulation, but treatment suffers reduce...

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Detalles Bibliográficos
Autores principales: Luo, Qiuhua, Shi, Wen, Wang, Puxiu, Zhang, Yu, Meng, Jia, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235205/
https://www.ncbi.nlm.nih.gov/pubmed/34208641
http://dx.doi.org/10.3390/pharmaceutics13060895