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Tin Mesoporphyrin Selectively Reduces Non-Small-Cell Lung Cancer Cell Line A549 Proliferation by Interfering with Heme Oxygenase and Glutathione Systems

In order to maintain redox homeostasis, non-small-cell lung cancer (NSCLC) increases the activation of many antioxidant systems, including the heme-oxygenase (HO) system. The overexpression of HO-1 has been often associated with chemoresistance and tumor aggressiveness. Our results clearly showed an...

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Detalles Bibliográficos
Autores principales: Sorrenti, Valeria, D’Amico, Agata Grazia, Barbagallo, Ignazio, Consoli, Valeria, Grosso, Salvo, Vanella, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235249/
https://www.ncbi.nlm.nih.gov/pubmed/34205698
http://dx.doi.org/10.3390/biom11060917