Preclinical Assessment of Ursolic Acid Loaded into Nanostructured Lipid Carriers in Experimental Visceral Leishmaniasis

Ursolic acid, a triterpene produced by plants, displayed leishmanicidal activity in vitro and in vivo; however, the low solubility of this triterpene limits its efficacy. To increase the activity of ursolic acid (UA), this triterpene was entrapped in nanostructured lipid carriers (UA-NLC), physical-...

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Detalles Bibliográficos
Autores principales: Jesus, Jéssica Adriana, Sousa, Ilza Maria Oliveira, da Silva, Thays Nicolli Fragoso, Ferreira, Aurea Favero, Laurenti, Márcia Dalastra, Antonangelo, Leila, Faria, Caroline Silvério, da Costa, Paulo Cardoso, de Carvalho Ferreira, Domingos, Passero, Luiz Felipe Domingues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235317/
https://www.ncbi.nlm.nih.gov/pubmed/34205283
http://dx.doi.org/10.3390/pharmaceutics13060908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235317/
https://www.ncbi.nlm.nih.gov/pubmed/34205283
http://dx.doi.org/10.3390/pharmaceutics13060908

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