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Interleukin-1β Induces Tissue Factor Expression in A549 Cells via EGFR-Dependent and -Independent Mechanisms

Tissue factor (TF) plays an important role in the progression and angiogenesis of tumor cells. The present study investigated the mechanism of interleukin-1β (IL-1β)-induced TF expression in A549 lung cancer cells. Based on mRNA and protein analyses, including appropriate inhibitor experiments, IL-1...

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Detalles Bibliográficos
Autores principales: Mechelke, Tobias, Wittig, Felix, Ramer, Robert, Hinz, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235322/
https://www.ncbi.nlm.nih.gov/pubmed/34205482
http://dx.doi.org/10.3390/ijms22126606