Concise Synthesis of Both Enantiomers of Pilocarpine

Furan-2-carboxylic acid was used as a starting material for the synthesis of dehydro-homopilopic acid. Esterification, hydrogenation and enzymatic hydrolysis followed by the reduction of Weinreb amides and a single-step attachment of a 1-methyl-imidazole residue allowed for the concise synthesis of...

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Detalles Bibliográficos
Autores principales: Schmidt, Theresa, Heise, Niels, Merzweiler, Kurt, Deigner, Hans-Peter, Al-Harrasi, Ahmed, Csuk, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235342/
https://www.ncbi.nlm.nih.gov/pubmed/34208623
http://dx.doi.org/10.3390/molecules26123676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235342/
https://www.ncbi.nlm.nih.gov/pubmed/34208623
http://dx.doi.org/10.3390/molecules26123676

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