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Does TBC1D4 (AS160) or TBC1D1 Deficiency Affect the Expression of Fatty Acid Handling Proteins in the Adipocytes Differentiated from Human Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Obtained from Subcutaneous and Visceral Fat Depots?

TBC1D4 (AS160) and TBC1D1 are Rab GTPase-activating proteins that play a key role in the regulation of glucose and possibly the transport of long chain fatty acids (LCFAs) into muscle and fat cells. Knockdown (KD) of TBC1D4 increased CD36/SR-B2 and FABPpm protein expressions in L6 myotubes, whereas...

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Detalles Bibliográficos
Autores principales: Mikłosz, Agnieszka, Łukaszuk, Bartłomiej, Supruniuk, Elżbieta, Grubczak, Kamil, Moniuszko, Marcin, Choromańska, Barbara, Myśliwiec, Piotr, Chabowski, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235367/
https://www.ncbi.nlm.nih.gov/pubmed/34208471
http://dx.doi.org/10.3390/cells10061515