Electrophysiology of hiPSC-Cardiomyocytes Co-Cultured with HEK Cells Expressing the Inward Rectifier Channel

The immature electrophysiology of human-induced pluripotent stem cell-derived cardiomyocytes (hiCMs) complicates their use for therapeutic and pharmacological purposes. An insufficient inward rectifying current (I(K1)) and the presence of a funny current (if) cause spontaneous electrical activity. T...

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Detalles Bibliográficos
Autores principales: Costa, Ana Da Silva, Mortensen, Peter, Hortigon-Vinagre, Maria P., van der Heyden, Marcel A. G., Burton, Francis L., Gao, Hao, Simitev, Radostin D., Smith, Godfrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235371/
https://www.ncbi.nlm.nih.gov/pubmed/34205607
http://dx.doi.org/10.3390/ijms22126621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235371/
https://www.ncbi.nlm.nih.gov/pubmed/34205607
http://dx.doi.org/10.3390/ijms22126621

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