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Electrophysiology of hiPSC-Cardiomyocytes Co-Cultured with HEK Cells Expressing the Inward Rectifier Channel
The immature electrophysiology of human-induced pluripotent stem cell-derived cardiomyocytes (hiCMs) complicates their use for therapeutic and pharmacological purposes. An insufficient inward rectifying current (I(K1)) and the presence of a funny current (if) cause spontaneous electrical activity. T...
Autores principales: | Costa, Ana Da Silva, Mortensen, Peter, Hortigon-Vinagre, Maria P., van der Heyden, Marcel A. G., Burton, Francis L., Gao, Hao, Simitev, Radostin D., Smith, Godfrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235371/ https://www.ncbi.nlm.nih.gov/pubmed/34205607 http://dx.doi.org/10.3390/ijms22126621 |
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