The CRBN, CUL4A and DDB1 Expression Predicts the Response to Immunomodulatory Drugs and Survival of Multiple Myeloma Patients

Immunomodulatory drugs (IMiDs) are effective in the treatment of multiple myeloma (MM), myelodysplastic syndrome with deletion of chromosome 5q and other haematological malignancies. Recent studies showed that IMiDs bind to cereblon (CRBN), a substrate receptor of the CRL4–CRBN complex, to induce th...

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Detalles Bibliográficos
Autores principales: Barankiewicz, Joanna, Szumera-Ciećkiewicz, Anna, Salomon-Perzyński, Aleksander, Wieszczy, Paulina, Malenda, Agata, Garbicz, Filip, Prochorec-Sobieszek, Monika, Misiewicz-Krzemińska, Irena, Juszczyński, Przemysław, Lech-Marańda, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235391/
https://www.ncbi.nlm.nih.gov/pubmed/34207079
http://dx.doi.org/10.3390/jcm10122683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235391/
https://www.ncbi.nlm.nih.gov/pubmed/34207079
http://dx.doi.org/10.3390/jcm10122683

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