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Estrogen-Like Effect of Mitotane Explained by Its Agonist Activity on Estrogen Receptor-α
Mitotane is the cornerstone of medical treatment of adrenocortical carcinoma. Estrogenic-like side effects frequently occur in patients, and previous studies explored the chemical nature of the interaction between estrogen receptor-α (ER-α) and toxic compounds, including the DDD derivatives. We used...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235434/ https://www.ncbi.nlm.nih.gov/pubmed/34208714 http://dx.doi.org/10.3390/biomedicines9060681 |