Methylglyoxal-Derived Advanced Glycation End Product (AGE4)-Induced Apoptosis Leads to Mitochondrial Dysfunction and Endoplasmic Reticulum Stress through the RAGE/JNK Pathway in Kidney Cells

Advanced glycation end products (AGEs) are formed via nonenzymatic reactions between reducing sugars and proteins. Recent studies have shown that methylglyoxal, a potent precursor for AGEs, causes a variety of biological dysfunctions, including diabetes, inflammation, renal failure, and cancer. Howe...

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Detalles Bibliográficos
Autores principales: Jeong, So-Ra, Lee, Kwang-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235496/
https://www.ncbi.nlm.nih.gov/pubmed/34207084
http://dx.doi.org/10.3390/ijms22126530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235496/
https://www.ncbi.nlm.nih.gov/pubmed/34207084
http://dx.doi.org/10.3390/ijms22126530

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