Cargando…

Methylglyoxal-Derived Advanced Glycation End Product (AGE4)-Induced Apoptosis Leads to Mitochondrial Dysfunction and Endoplasmic Reticulum Stress through the RAGE/JNK Pathway in Kidney Cells

Advanced glycation end products (AGEs) are formed via nonenzymatic reactions between reducing sugars and proteins. Recent studies have shown that methylglyoxal, a potent precursor for AGEs, causes a variety of biological dysfunctions, including diabetes, inflammation, renal failure, and cancer. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeong, So-Ra, Lee, Kwang-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235496/ https://www.ncbi.nlm.nih.gov/pubmed/34207084 http://dx.doi.org/10.3390/ijms22126530

Ejemplares similares

The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs
por: Xue, Jing, et al.
Publicado: (2014)

Methylglyoxal induces cell death through endoplasmic reticulum stress‐associated ROS production and mitochondrial dysfunction
por: Chan, Chi‐Ming, et al.
Publicado: (2016)

Advanced Glycation End-Product Precursor Methylglyoxal May Lead to Development of Alzheimer’s Disease
por: Li, Wai Yin, et al.
Publicado: (2022)

The Receptor for Advanced Glycation End Products (RAGE) and the Lung
por: Buckley, Stephen T., et al.
Publicado: (2010)

Involvement of Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in Advanced Glycation End Products-Induced Glomerular Mesangial Cell Injury
por: Chiang, Chih-Kang, et al.
Publicado: (2016)

Advanced glycation end products (AGEs) and their receptor (RAGE) induce apoptosis of periodontal ligament fibroblasts
por: Li, D.X., et al.
Publicado: (2014)

Stigmasterol Causes Ovarian Cancer Cell Apoptosis by Inducing Endoplasmic Reticulum and Mitochondrial Dysfunction
por: Bae, Hyocheol, et al.
Publicado: (2020)

Early Progression of Diabetic Nephropathy Correlates With Methylglyoxal-Derived Advanced Glycation End Products
por: Beisswenger, Paul J., et al.
Publicado: (2013)

Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway
por: Wu, Yu-Jen, et al.
Publicado: (2019)

Role of receptor for advanced glycation end products (RAGE) in liver disease
por: Yamagishi, Sho-ichi, et al.
Publicado: (2015)

Hypoxia and the Receptor for Advanced Glycation End Products (RAGE) Signaling in Cancer
por: Taneja, Sakshi, et al.
Publicado: (2021)

Leptin and advanced glycation end products receptor (RAGE) in tuberculosis patients
por: Lazzari, Tássia Kirchmann, et al.
Publicado: (2021)

The Potential Influence of Advanced Glycation End Products and (s)RAGE in Rheumatic Diseases
por: Delrue, Charlotte, et al.
Publicado: (2023)

Enhanced Formation of Methylglyoxal-Derived Advanced Glycation End Products in Arabidopsis Under Ammonium Nutrition
por: Borysiuk, Klaudia, et al.
Publicado: (2018)

Ethyl Pyruvate Prevents Renal Damage Induced by Methylglyoxal-Derived Advanced Glycation End Products
por: Jung, Eunsoo, et al.
Publicado: (2019)

RAGE-Dependent Effect of Exogenous Methylglyoxal Intake on Lung Biomechanics in Mice
por: Al-Robaiy, Samiya, et al.
Publicado: (2022)

Glycation of paraoxonase 1 by high glucose instigates endoplasmic reticulum stress to induce endothelial dysfunction in vivo
por: Yu, Wei, et al.
Publicado: (2017)

Enriched endoplasmic reticulum-mitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice
por: Zhao, Lihong, et al.
Publicado: (2017)

Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo
por: Kim, Junghyun, et al.
Publicado: (2012)

Diacerein ameliorates cholestasis-induced liver fibrosis in rat via modulating HMGB1/RAGE/NF-κB/JNK pathway and endoplasmic reticulum stress
por: Abdelfattah, Amira Mohammed, et al.
Publicado: (2023)

Methylglyoxal Induces Mitochondrial Dysfunction and Cell Death in Liver
por: Seo, Kyuhwa, et al.
Publicado: (2014)

Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis
por: Wetzels, Suzan, et al.
Publicado: (2017)

The Role of Receptor for Advanced Glycation End Products (RAGE) in the Proliferation of Hepatocellular Carcinoma
por: Yaser, Al-Madhagi, et al.
Publicado: (2012)

The Receptor for Advanced Glycation End Products (RAGE) Contributes to the Progression of Emphysema in Mice
por: Sambamurthy, Nisha, et al.
Publicado: (2015)

The Receptor for Advanced Glycation End Products (RAGE) Is Associated with Persistent Atrial Fibrillation
por: Lancefield, Terase F., et al.
Publicado: (2016)

Receptor for advanced glycation end-products (RAGE) mediates phagocytosis in nonprofessional phagocytes
por: Yang, Yan, et al.
Publicado: (2022)

Receptor for the Advanced Glycation End Products (RAGE) Pathway in Adipose Tissue Metabolism
por: Gutowska, Klaudia, et al.
Publicado: (2023)

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands
por: Yao, Dachun, et al.
Publicado: (2010)

Endoplasmic reticulum stress and apoptosis
por: Faitova, Jitka, et al.
Publicado: (2006)

Hyperoside Downregulates the Receptor for Advanced Glycation End Products (RAGE) and Promotes Proliferation in ECV304 Cells via the c-Jun N-Terminal Kinases (JNK) Pathway Following Stimulation by Advanced Glycation End-Products In Vitro
por: Zhang, Zhengyu, et al.
Publicado: (2013)

Polymorphisms −374 T/A and −429 T/C of the Receptor for Advanced Glycation End-Products (RAGE) and Serum Levels of RAGE (sRAGE) Are Not Associated with Metabolic Syndrome
por: González-Guerrero, Diana Elizabeth, et al.
Publicado: (2023)

The Receptor for Advanced Glycation End-products (RAGE) Sustains Autophagy and Limits Apoptosis, Promoting Pancreatic Tumor Cell Survival
por: Kang, Rui, et al.
Publicado: (2009)

Inhibitory effect of herbal medicines and their trapping abilities against methylglyoxal-derived advanced glycation end-products
por: Sompong, Weerachat, et al.
Publicado: (2015)

On the Role of Aminochrome in Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Parkinson's Disease
por: Segura-Aguilar, Juan
Publicado: (2019)

Endoplasmic reticulum stress and mitochondrial dysfunctions in metal-induced neurological pathology
por: Cai, Sophia, et al.
Publicado: (2022)

Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis
por: Yedida, Govindaraju, et al.
Publicado: (2019)

The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress
por: Yang, Tzu-Yen, et al.
Publicado: (2018)

Homocysteine Induces Apoptosis of Human Umbilical Vein Endothelial Cells via Mitochondrial Dysfunction and Endoplasmic Reticulum Stress
por: Zhang, Zhimin, et al.
Publicado: (2017)

In Patients with Chronic Kidney Disease Advanced Glycation End-Products Receptors Isoforms (sRAGE and esRAGE) Are Associated with Malnutrition
por: Caldiroli, Lara, et al.
Publicado: (2022)

Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance
por: Rodrigues, Tiago, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ao5voqk0url1ijup7g6lhjtas6