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Satellite Subgenomic Particles Are Key Regulators of Adeno-Associated Virus Life Cycle

Historically, adeno-associated virus (AAV)-defective interfering particles (DI) were known as abnormal virions arising from natural replication and encapsidation errors. Through single virion genome analysis, we revealed that a major category of DI particles contains a double-stranded DNA genome in...

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Detalles Bibliográficos
Autores principales: Zhang, Junping, Yu, Xiangping, Guo, Ping, Firrman, Jenni, Pouchnik, Derek, Diao, Yong, Samulski, Richard Jude, Xiao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235507/
https://www.ncbi.nlm.nih.gov/pubmed/34205760
http://dx.doi.org/10.3390/v13061185