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Satellite Subgenomic Particles Are Key Regulators of Adeno-Associated Virus Life Cycle
Historically, adeno-associated virus (AAV)-defective interfering particles (DI) were known as abnormal virions arising from natural replication and encapsidation errors. Through single virion genome analysis, we revealed that a major category of DI particles contains a double-stranded DNA genome in...
Autores principales: | Zhang, Junping, Yu, Xiangping, Guo, Ping, Firrman, Jenni, Pouchnik, Derek, Diao, Yong, Samulski, Richard Jude, Xiao, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235507/ https://www.ncbi.nlm.nih.gov/pubmed/34205760 http://dx.doi.org/10.3390/v13061185 |
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