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Engineering of the CHAPk Staphylococcal Phage Endolysin to Enhance Antibacterial Activity against Stationary-Phase Cells

Bacteriophage endolysins and their derivatives have strong potential as antibacterial agents considering the increasing prevalence of antibiotic resistance in common bacterial pathogens. The peptidoglycan degrading peptidase CHAPk, a truncated derivate of staphylococcal phage K endolysin (LysK), has...

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Detalles Bibliográficos
Autores principales: Arroyo-Moreno, Sara, Begley, Máire, Dembicka, Kornelia, Coffey, Aidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235606/
https://www.ncbi.nlm.nih.gov/pubmed/34208478
http://dx.doi.org/10.3390/antibiotics10060722